TOP2A and hepatocellular carcinoma: Hence, we further evaluated the specificity and sensitivity of the six genes in the diagnosis of their AUC values from high to low, namely: CDCA5 (AUC = 0.978), CDC20 (AUC = 0.957), NCAPG (AUC = 0.931), PRC1 (AUC = 0.903), TOP2A (AUC = 0.886), and PBK (AUC = 0.839), implying that they all had acceptable specificity and sensitivity as diagnostic markers for HCC (Figure 5J).