DMD and Duchenne muscular dystrophy: Since the snRNA is produced by a donor nucleus, assembles in the cytoplasm and then enters all the neighbouring nuclei, this mechanism amplifies several folds the production of dystrophin both in vitro and in immune deficient DMD mice with a skippable mutation of exon 51 (Galli et al. in preparation) resulting in a much higher production of dystrophin than when healthy cells, that can only produce their own dystrophin, are injected.