SERPINE1 and myeloid sarcoma: Positive correlation of PAI-1 with waist circumference in pre-MS, as well as positive correlation of PAI-1 with HOMA IR and glycaemia and negative correlation with HDL-cholesterol in children and adolescents with MS indicate that visceral fat tissue may be a connection between elevated PAI-1 values ​​and IR in patients with pre-MS and MS (Dimitrijevic-Sreckovic et al., 2007).