The LinkInterpreter module was used for Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis of genes coexpressed with RNF169, which showed that the coexpressed genes in PAAD are involved in the Janus kinase (JAK)-signal transducer of activators of transcription (STAT) signaling pathway, tumour necrosis factor (TNF) signaling pathway, Toll-like receptor signaling pathway and pathways in cancer (Figure 7I). The gene discussed is TNF; the disease is cancer.