The mice knocked out circRNA CDR1as could make abnormal neural activities and behavioral disorders, show a phenotype associated with neuropsychiatric disorders—impaired PPI, and also affected mRNAs encoding proteins involved in the maintenance of the mouse sleep-wake cycle. The study provides indirect evidence for the possible involvement of CDR1as in the pathogenesis of schizophrenia. Here, LINC00632 is linked to schizophrenia.