Tail vein injection of SC-derived hepatocytes or SC-derived extracellular vesicles to animal with liver injuries had attenuated collagen deposition, liver fibrosis, and extracellular matrix alteration, it had decreased AST, ALT, increased serum ALB concentration, produced CK-18, enhanced liver regeneration and repair, and prolonged recipient survival [9, 40–42]. The gene discussed is ALB; the disease is Hepatic fibrosis.