Moreover, we detected several inflammatory factors in the plasma of AD, including IFN-gamma, IL-18, IL-1beta, IL-13, IL-8, IL-7, CCL11, MCP-1, TSLP, IL-10, BDNF, IL-17, IL-5, and TREM-1 (Supplementary Table 2). The gene discussed is BDNF; the disease is Alzheimer disease.