CD4 and juvenile idiopathic arthritis: The frequency of CD4+PD-1intCXCR5- cells was increased in the SF of oligo JIA patients compared to the PB of patients and controls, but no significant difference was detected between ANA+ (42.4 ± 4.2%) and ANA- (48.3 ± 3.1%) SF samples (p-value = 0.75) (Figures 1A, B).