DEA of Tph-like Tregs versus other Tregs confirmed that these cells in oligo JIA SF share key markers with Tph and other CD4+ T cells that help B cells, including PDCD1, CD40LG, CXCL13, IL21, SH2D1A/SAP and MAF (Figures 6D, E). The gene discussed is IL21; the disease is juvenile idiopathic arthritis.