The parallel downregulation of multiple genes which have been associated with increased metastasis and poor prognosis in CRC was observed, including Dachshund family transcription factor 1 (DACH1) (52) and the metalloprotease meprin-α (MEP1A) (53) and CXCL14 (54). The gene discussed is CXCL14; the disease is colorectal carcinoma.