Anti-SSA and anti-SSB were the predominant autoantibodies of cluster 2 and were associated with SjS [anti-SSA (OR: 6.501, 95% CI: 2.600-16.253, P<0.0001), anti-SSB (OR: 27.958, 95% CI: 4.954-157.777, P=0.0002)]. This evidence concerns the gene TRIM21 and Schwartz-Jampel syndrome.