SOCS3 and pneumonia: (29) found that GAS5 mRNA expression was significantly decreased in hMDMs from children with pneumonia and this is accompanied by increased M2 phenotype macrophages compared with the control group, and GAS5 overexpression promoted macrophage polarization from M2 to M1 in children with pneumonia via the miR-455-5p/SOCS3/JAK2/STAT3 axis, indicating its protective role in pneumonia in children.