SQSTM1 and renal fibrosis: Followed by our previous study that STAT6 activation negatively regulates PPARα signaling and causes FAO disorder and aggravates renal fibrosis (5), here we found that Cana attenuates renal tubular cells’ FAO disorder and renal fibrosis by SQSTM1/autophagy-mediated STAT6 degradation in an m6A-dependent manner.