reported a panel of seven cytokines, including receptor for advanced glycation end-products (RAGE), procollagen peptide III (PCPIII), brain natriuretic peptide (BNP), angiopoietin-2 (Ang-2), interleukin-10 (IL-10), tumor necrosis factor alpha (TNF-α) and interleukin-8 (IL-8), with high diagnostic accuracy for ARDS occurrence (4). This evidence concerns the gene TNF and acute respiratory distress syndrome.