PGC and gastric cancer: We re-clustered 6,157 epithelial cells and found 7 subtypes in GC tumors (Figures 4A-C), including chief cells (marked by PGC and LIPF), enterocytes (FABP1 and ANPEP), enteroendocrine cells (CHGA and TPH1), goblet cells (MUC2), metaplastic stem-like cells (EPHB2 and SOX9), pit mucous cells (MUC5AC and TFF1) and proliferative cells (MKI67 and BIRC5, Figure 4D, Figure S3).