The correlation between liver fibrosis stage and age (P < 0.001, r = 0.32), TBIL (P = 0.008, r = 0.23), CHE (P < 0.001, r =-0.30), PLT (P < 0.001, r =-0.40), PTA (P = 0.046, r =-0.22) and INR (P = 0.04, r = 0.23) were significant, while the correlation with HBsAg, ALT, AST, and ALB were not significant. The gene discussed is ALB; the disease is Hepatic fibrosis.