AFP and cirrhosis of liver: Using an appropriate cut-off value, the AUC of MALAT1 expression level used to distinguish patients with or without liver cirrhosis was 0.631 (cut-off value 3.86, p = 0.006; Table 4; Figure 15A), 0.676 for patients with or without vascular invasion (cut-off value 54.52, p < 0.001; Figure 15B), 0.605 for patients with or without tumor capsule infiltration (cut-off value 54.52, p = 0.039; Figure 15C), and 0.593 for patients positive or negative for AFP (cut-off value 4.23, p = 0.037; Figure 15D).