When compared with participants without diabetes during follow-up, participants who developed diabetes were older, more likely to be male, had greater values of BMI, SBP, DBP, TC, TG, had lower levels of HDL-C, AST/ALT ratio, had a higher proportion of current smoker and drinker, and more likely to have the family history of diabetes (P < 0.05; Table 2). The gene discussed is GPT; the disease is diabetes mellitus.