Additionally, immune-related pathways such as B cell receptor signaling pathway, graft-vs.-host disease, legionellosis, leishmaniasis, and rheumatoid arthritis were significantly enriched in the high ACSL1 subgroup (Figure 8A), while metabolism-related pathways such as butanoate metabolism, linoleic acid metabolism, and taurine and hypotaurine metabolism were significantly enriched in the low ACSL1 subgroup (Supplementary Figure 2A). Here, ACSL1 is linked to leishmaniasis.