In addition, these genes were particularly associated with IL-17 signaling pathway, TNF signaling pathway, lipid and atherosclerosis, toll-like receptor signaling pathway, C-type lectin receptor signaling pathway, legionellosis, osteoclast differentiation, rheumatoid arthritis and NF-kappa B signaling pathway in the KEGG enrichment analysis (Figures 4C–E). Here, TNF is linked to rheumatoid arthritis.