IL1R2 and type 2 diabetes mellitus: B cell receptor signaling pathway, fc gamma R-mediated phagocytosis, legionellosis, leishmaniasis and osteoclast differentiation were significantly enriched in the high IL1R2 subgroup (Figure 8C), whereas linoleic acid metabolism, taurine and hypotaurine metabolism, and maturity onset diabetes of the young were significantly enriched in the low IL1R2 subgroup (Supplementary Figure 2C).