While ApoB-containing lipoproteins, inflammatory biomarkers, and markers of endothelial dysfunction and fibrosis were all associated with human coronary atherosclerosis, triglyceride-rich LDL particles, as measured by LDL-TG levels, emerged as a potentially key factor, within a sub-network that includes apoB and LDL-C. This evidence concerns the gene APOB and coronary atherosclerosis.