SELP and COVID-19: A common characteristic of patients with advanced COVID-19 disease is thrombocytopenia (5, 25–27); COVID-19 lungs show increased number of pulmonary megakaryocytes, which could be indicative of increased local megakaryopoiesis in response to platelet consumption (28); SARS-CoV-2 infection is associated with platelet hyperreactivity, including increased P-selectin expression, platelet activation and spreading on both fibrinogen and collagen, and elevated levels of circulating platelet-neutrophil, -monocyte, and -T-cell aggregates (29–32).