CSPG4 and melanoma: MTEX isolation from total plasma exosomes was performed by immune capture using the melanoma cell-specific monoclonal Abs provided by Dr. Soldano Ferrone (Harvard U.)Anti-CSPG4 mAbs (clones 763.64 and 225.28) recognize an epitope of CSPG4 (also known as the high molecular weight melanoma associated antigen) present on melanoma cells but not on any other non-malignant cells or tissues as determined by immunostaining and previously reported (Campoli et al., 2004).