Recently, the research revealed that BMSCs-derived exosomal miR-19b-1-5p could inhibit bladder cancer cell lines (T24, UC3, 5637, and J82) from migrating, proliferating, or invading while promoting cell death via inhibiting ABL2, Bcl-2, MMP2 and MMP9 (Fu et al., 2021). This evidence concerns the gene BCL2 and urinary bladder cancer.