Results showed that deletion of PRC1 inhibited bladder cancer cells’ ability to proliferate and spread, as well as halted the induction of EMT, which was shown by changes in the production of E-cadherin, and Bax and decreases in the synthesis of N-cadherin, Vimentin, SNAIL, Bcl-2, and PCNA. The gene discussed is BCL2; the disease is urinary bladder carcinoma.