PLK5 and neoplasm: According to the multivariable Cox regression analysis for DFS, tumor PLK5 protein expression (high vs. low) [hazard ratio (HR) = 0.573, P = 0.022] was independently related to prolonged DFS, whereas higher pathological grade (HR = 1.344, P = 0.024) and ECOG PS score (1 vs. 0) (HR = 2.185, P < 0.001) were both independently linked with shorter DFS.