Among the variants that found by ASSET to be shared between CAD and longevity, ING1 (rs9583531, locus 18) encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis, is responsible for implementation of senescence and the reduced expression and rearrangement of this gene have been detected in various cancers (76). The gene discussed is ING1; the disease is coronary artery disorder.