TNFSF10 and cancer: Although there are many drugs used in cancer therapy, the most widely investigated is doxorubicin (DOX) alone [104, 105] or combined with other therapeutic agents, e.g. paclitaxel (PXT) [106], miR-519c (microRNA to improve intracellular concentration of chemotherapeutic drugs) [107], TRAIL ((TNF)-related apoptosis-inducing ligand) [91] or p53 (gene-therapeutic agent) [90].