Another study that transplanted visceral fat from young donor mice directly onto the carotid artery of young ApoE−/− mice, a murine model of atherosclerosis (Daugherty et al., 2017), found that the fat transplant enhanced atherosclerosis within the carotid artery, a phenotype associated with increased serum CCL2 levels (Ohman et al., 2011). This evidence concerns the gene CCL2 and atherosclerosis.