CDK1 and infection: As for HPV16 PsV infection, transformation of keratinocytes was completely abrogated, when cells were infected with HPV16 SSTP212AAAA quasiviruses, whereas HPV16 T265A exhibited no colonies for two different keratinocyte donors and drastically reduced colonies for an additional donor (Figs. 6C, D) highlighting the importance of CDK1 and PLK1 for HPV16 infection and subsequent persistence.