In addition, fused in sarcoma (FUS), heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1), and TAR DNA-binding protein of 43 kDa (TDP-43) are found in the pathological inclusions of amyotrophic lateral sclerosis patients participating in stress granule formation via LLPS to regulate the metabolism of RNA (9, 10, 11). The gene discussed is HNRNPA1; the disease is amyotrophic lateral sclerosis.