For example, BAX expression among cancer cells is lowest in upper aerodigestive lineages (UAD) and highest in fibroblast lineages; CDKN1A is lowest in blood and highest in fibroblasts; GDF15 is lowest in lymphocytes and highest in kidney; and MDM2 is lowest in thyroid lineages and highest in cervix (Fig. S1A). Here, CDKN1A is linked to cancer.