Given previous works by Kagoya et al., Zhu et al., and Hogg et al. which established the role for BETi in maintaining stemness of CD8+ T cells via inhibition of TCR-activated transcription factor BATF [33] and that BETi reduce immunosuppressive ligand PDL1 [31, 32] expression, we asked whether BETi + anti-PD1 could impact the exhausted phenotype found in T cells from our AML mice. This evidence concerns the gene BATF and acute myeloid leukemia.