PARK2+E mice had significantly higher visuospatial memory (58.45 ± 2.94 SEM, p = 0.02) (Fig. 6e), discrimination index (DI) (0.29 ± 0.06 SEM, p = 0.03) (Fig. 6f), and decreased anxiety-like behavior (1.61 ± 0.08 SEM, p = 0.04) (Fig. 6g, h) compared to PARK2 mice receiving vehicle (49.97 ± 2.52 SEM, 0.09 ± 0.05 SEM, 2.12 ± 0.21 SEM respectively). Here, PRKN is linked to Anxiety.