Finally, we evaluated whether rotenone affected the serum glucose concentration in PARK2 mice and found that PARK2+R mice had hyperglycemia (8.26 ± 0.37 SEM) compared to PARK2+V mice (6.39 ± 0.93 SEM, p = 0.04) (Fig. 7h). Here, PRKN is linked to Hyperglycemia.