In gastrointestinal cancer, high expression level of NCF2 was associated with the poor prognosis of esophageal squamous cell carcinoma,23 and Zhang et al. revealed that upregulation of NCF2 promoted the angiogenesis and metastasis of gastric cancer through NF‐κB pathway.24 This evidence concerns the gene NCF2 and esophageal squamous cell carcinoma.