To reach this goal, researchers evaluate different strategies, such as increasing the chemokine secretion of tumor cells by radiation or improving the inherent migration ability of hMSCs by increasing the expression of proteins relevant for their homing such as the C-X-C chemokine receptor type 4 (CXCR-4) [52,57,58,59,60,61]. Here, CXCR4 is linked to neoplasm.