ANGPT2 and hepatocellular carcinoma: The univariate Cox regression analysis revealed that age ≥75 years, M2BPGi ≥ 4.23, AFP ≥ 7.7 ng/mL, Ang2 ≥ 464 pg/mL, and diabetes were significantly associated with HCC occurrence after successful HCV eradication by DAAs (Table 2).