A comparison of cumulative incidences of HCC occurrence (%) revealed that patients with baseline serum Ang2 level < 464 pg/mL had a significantly lower risk of HCC incidence than those with baseline serum Ang2 level ≥ 464 pg/mL (p = 0.0027) (Figure 2A). Here, ANGPT2 is linked to hepatocellular carcinoma.