The median analysis indicated that the levels of serum Arp2 in the 48 schizophrenia patients were substantially decreased than that in 36 normal individuals (5909.18 ± 1041.07 ng/L versus 7216.01 ± 2408.58 ng/L respectively; p < 0.01) (Figure 1F, Table S8). Here, ACTR2 is linked to schizophrenia.