Additionally, in a recent study conducted by Maruyama et al. [76] in mouse LF model in which they evaluated the auditory function employing auditory brainstem response (ABR) and distortion product otoacoustic emissions (DPOAE) in determination of the underlying mechanisms of LASV-induced hearing loss; they pioneered measures of ABR and DPOAE tests in rodents in biosafety level 4 (BSL-4) facilities and concluded that depletion of T cell indicated that CD4 T-cells play crucial function in hearing loss induced by LASV. Here, CD4 is linked to hearing loss disorder.