ISG15 and infection: Neurons and astrocytes are not the only cell types playing important roles during RABV infection: here, we identified the upregulation of IFN-inducible genes with antiviral responses (CXCL10, ISG15, and MX1) in hiMicros (Figure 3) as well as a modest increase in IL-6 protein expression in microglial-like cells upon Tha and Th2P-4M infection (Figure 4).