CCL2 and Epstein-Barr virus infection: Two additional studies further demonstrated that EBV induced a TLR2-dependent response resulting in production of inflammatory cytokines/chemokines including IL-8 and monocyte chemoattractant protein 1 (MCP-1) [73,74] and the anti-inflammatory cytokine, IL-10 [73] in primary human monocytes [73] and THP-1-differentiated macrophages [74] potentially contributing to tumorigenesis associated with EBV infection.