These findings come alongside our observations that the patients without respiratory failure had more baseline CD4+ and CD8+ T-lymphocytes (compared to those with severe COVID-19) and a pronounced increase in activated and memory CD4+ T-cells and total and activated CD8+ T-cells over time was observed in the patients treated with dexamethasone who reached convalescence, but not in those who failed to recover. This evidence concerns the gene CD8A and respiratory failure.