SOAT1 and acute disseminated encephalomyelitis: Intriguingly, the KEGG pathways analysis of all the DEPs also revealed that four signaling pathways have changed in PAMs with a PRRSV-ADE infection, including the toll-like receptor signaling pathway, the NOD-like receptor signaling pathway, the RIG-I-like receptor signaling pathway and the JAK-STAT signaling pathway.