LTF and Parkinson disease: Bollimpelli et al. [62] studied the neuroprotective effects of CUR-loaded lactoferrin nanoparticles on rotenone-induced PD in dopaminergic cell line SK-NSH pretreated with CUR in solution, nanoCUR equivalent or lactoferrin nanoparticles (deprived of CUR), in addition to being subsequently treated with rotenone for induction of neurotoxicity.