CTSG and Insulin resistance: These findings are in accordance with previous studies that analyzed the individual Cγ effect to reduce the proinflammatory response and insulin resistance in PANC-1 cells, through the modulation of INF-γ expression, cytokines (IL-6, IL-12P70, IL-17A, and IL-27), and ROS levels, as well as an increase in antioxidant molecules [20,58].