GCG and Insulin resistance: Using the Kyoto Encyclopedia of Genes and Genomes (KEGG), we performed an analysis of the pathways and detected: 12 targets involved in metabolic pathways, eight in cancer, seven in MAPK signaling, six in PI3K/Akt signaling, six in Foxo, six in apoptosis, five in AMPK signaling, five in glucagon signaling, and four in insulin resistance.