MM418-C1 melanoma cells containing the BRAFV600E oncogene as well as D24 melanoma cells containing BRAFWT were used to test for specific cytotoxic effects of M. cochinchinensis extracts on BRAF mutation, while human immortalised keratinocytes (HaCaT) was used to compare the cytotoxicity of the extracts on a non cancerous epithelial cell. Here, BRAF is linked to melanoma.