Furthermore, the fact that the plasma of the immunized animals recognized the S. mansoni total proteins (STP) proved that the antibodies produced from the immunization with the recombinant S. mansoni enzymes AK, HGPRT and MIX are capable to recognize and bind to adult worms, potentiating the control of this infection by paths not yet clarified for this model. Here, MIXL1 is linked to infection.