CD4 and chronic obstructive pulmonary disease: An analysis of the subtypes of airway immune cells in MLN, BALF, and lung in COPD-induced mice through FACS confirmed that SGE inhibited the elevation in the number of activated T lymphocytes (CD4+, CD8+, CD4+/CD69+, CD8+/CD69+, CD62L−/CD44high+) and neutrophils (Gr-1+/siglecF−).