A previous in vitro study showed that in mononuclear cells, a multivitamin complex rich in b-carotenes, vitamin C, and tocopherol had an antioxidant and anti-inflammatory effect in patients with type 1 diabetes and decreased the production of proinflammatory cytokines IL6 and TNF-α and increased IL4 [41]. The gene discussed is IL6; the disease is type 1 diabetes mellitus.