The GOF mutations of KCa2.3 are linked with the Zimmermann–Laband syndrome (ZLS) [60,62,63,64] and have also been associated with an idiopathic non-cirrhotic portal hypertension (INCPH) [60,62,65], In one study [66], CAG repeat polymorphism in KCNN3 was linked to schizophrenia. The gene discussed is KCNN3; the disease is Zimmermann-Laband syndrome.