MPL and autoimmune thrombocytopenic purpura: There are various alternatives to the use of IVIG in ITP, including thrombopoietin receptor agonists (TPOS-Ras; Eltrombopag and Avatrombopag), anti-D, spleen tyrosine kinase (Syk) inhibitors (fostamatinib), and splenectomy [17,18,19,20].