SOD1 and metabolic syndrome: Jeong et al. (2012) reached a similar conclusion that quercetin (MH6) could significantly reduce the content of MDA in C57BL/KsJ db/db mice, and increase the activities of SOD, CAT, and GSH-Px, which had a good effect on improving the hyperglycemia, dyslipidemia, and antioxidant status of T2DM [72] (Figure 5).