G6PC1 and diabetes mellitus: Furthermore, phlorizin (MH1) could also reduce the liver index, epididymis, and white adipose tissue index around the kidney, and increase the pancreas index of diabetes mice and the levels of glycerol kinase (GK) and glycogen in the liver, and reduce the activities of PEPCK and G-6-Pase, and effectively improve the symptoms of diabetes [54].