In U87 glioblastoma cells, chemotactic migration induced by TGF-β was suppressed by silencing either MT1-MMP or epithelial-mesenchymal transition-related protein SNAIL together with the reduced phosphorylation of decapentaplegic homolog (Smad)2/3 and STAT3 [103]. This evidence concerns the gene MMP14 and glioblastoma.